The report “Urea Cycle Disorders Treatment Market – Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2017 – 2025 “, has been prepared based on an in-depth market analysis with inputs from industry experts.
The objectives of this study are as follows:
To define, describe, and forecast the “Urea Cycle Disorders Treatment” market by type, application, component, delivery model, end user, and region
To provide detailed information regarding major factors influencing market growth (drivers, restraints, opportunities, and industry-specific challenges)
To analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
To forecast the market size of market segments with respect to the four key regions: North America, Europe, Asia, and the Rest of the World (RoW)
To strategically profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
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Urea Cycle Disorder (UCD) is an assembly of rare genomic ailment which affects approximately 3,000 – 7000 people every year in the U.S. UCD is triggered by an alteration in genes, which causes insufficiency of any of the six vital enzymes essential for the urea cycle. Urea cycle includes a sequence of biochemical steps in which one of the waste products of protein metabolism (nitrogen) in blood is removed and progressively converted into a compound called urea. In end, urea in the blood is removed the body as urine. In UCD, nitrogen amasses in the form of ammonia, which is a highly poisonous substance for the body. It results into a precarious condition called hyperammonia (elevated levels of ammonia in blood). If the ammonia enters the brain cells via blood, it can lead to coma, irremediable brain damage, or in serious condition death.
According to reports published by the CDC (Centers for Disease Control and Prevention), the anticipated incidence of UCD is 1 in 8500 births. Research findings suggest that many of the cases of UCD persist undiagnosed. In some of the cases, the newborn with UCD dies without a conclusive diagnosis. The precise global incidence of such cases is underrated or unknown. Some of the scientists in Europe suggest that Sudden Infant Death Syndrome (SIDS) cases might be due to an unknown inborn error of metabolism, for example, UCD. These scenarios are anticipated to drive the urea cycle disorders treatment market in the next few years. Additionally, research & development initiatives undertaken by research & academic institutes supported by pharmaceutical companies as well as governments are estimated to drive the global urea cycle disorders treatment market. Consequently, want of diagnosis & treatment options, unavailability of skilled personnel, and lack of reimbursement policies in developing countries are some of the factors hindering the growth of global urea cycle disorders treatment market. The UCD treatment market is less competitive as compared to other markets as UCD is a rare disorder and no conclusive research regarding it has been conducted so far. Government and pharmaceutical companies need to create awareness in the market and collaborative approaches should be undertaken.
The global urea cycle disorders treatment market can be divided based on type of treatment, enzyme deficiency type, delivery channels, and region. On the basis of treatment type, the global urea cycle disorders treatment market can be classified into amino acid formulas, phenylbutyrate, sodium benzoate, and others. In terms of enzyme deficiency type, the global urea cycle disorders treatment market can be segregated into Carbamyl Phosphate Synthetase (CPS1), N-Acetylglutamate Synthetase (NAGS), Ornithine Transcarbamylase (OTC Deficiency), Argininosuccinic Acid Synthetase (AS), Argininosuccinate Lyase (AL or ASA Lyase), Arginase (AG).
Based on delivery channel, the global urea cycle disorders treatment market can be segmented into hospital pharmacies, retail pharmacies, and online pharmacies.
Geographically, the global urea cycle disorders treatment market can be bifurcated into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The urea cycle disorders treatment market in North America is projected to expand rapidly in the next few years owing to the well-developed health care system, appropriate reimbursement scenario, and acceptance of the latest techniques in the region. Following North America, the urea cycle disorders treatment market in Europe and Asia Pacific is anticipated to expand rapidly during the forecast period. Existence of well-established players, rise in investments in research and development by pharmaceutical giants, association of pharmaceutical and biotech companies with research institutes are some of drivers of the global urea cycle disorders treatment market.
Key players operating in the urea cycle disorders treatment market include Horizon Pharma plc. Lucane Pharma, Recordati Rare Diseases Inc., and Synlogic.
The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.
The study is a source of reliable data on:
Market segments and sub-segments
Market trends and dynamics
Supply and demand
Value chain and stakeholder analysis
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The regional analysis covers:
North America (U.S. and Canada)
Latin America (Mexico, Brazil, Peru, Chile, and others)
Western Europe (Germany, U.K., France, Spain, Italy, Nordic countries, Belgium, Netherlands, and Luxembourg)
Eastern Europe (Poland and Russia)
Asia Pacific (China, India, Japan, ASEAN, Australia, and New Zealand)
Middle East and Africa (GCC, Southern Africa, and North Africa)
The report has been compiled through extensive primary research (through interviews, surveys, and observations of seasoned analysts) and secondary research (which entails reputable paid sources, trade journals, and industry body databases). The report also features a complete qualitative and quantitative assessment by analyzing data gathered from industry analysts and market participants across key points in the industry’s value chain.
A separate analysis of prevailing trends in the parent market, macro- and micro-economic indicators, and regulations and mandates is included under the purview of the study. By doing so, the report projects the attractiveness of each major segment over the forecast period.
Highlights of the report:
A complete backdrop analysis, which includes an assessment of the parent market
Important changes in market dynamics
Market segmentation up to the second or third level
Historical, current, and projected size of the market from the standpoint of both value and volume
Reporting and evaluation of recent industry developments
Market shares and strategies of key players
Emerging niche segments and regional markets
An objective assessment of the trajectory of the market
Recommendations to companies for strengthening their foothold in the market
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