Global Cancer Gene Therapy Market: Snapshot
Gene therapy is a massive and swiftly expanding field that could hold promising cures and treatments for several diseases and genetic problems. One of the more innovative segments in gene therapy falls under cancer treatment. It is one of the widely researched aspects of gene therapy, and thanks to increasing interest and investments from both government and private organizations, is showing a swift rate of development towards actually becoming a feasible and strong treatment alternative for cancer. These treatment options could be used to save a large number of lives of patients who are suffering from cancer, a disease that is causing one of the leading causes of deaths.
Of the several types of gene therapy approaches, the more promising ones include gene transfer, oncolytic virotherapy, and immunotherapy. The latest versions of vaccines being developed for cancer using gene therapy, are also expected to show an optimistic rate of development. These vaccines could potentially be used against malignant melanoma, prostate cancer, pancreatic cancer, and lung cancer, to name a few. Gene therapy involves modifying the genetic information in materials in order to effectively devise a cure.
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Global Cancer Gene Therapy Market: Overview
Cancer results from the multiple mutations in a single cell that makes it to proliferate out of control. Cancer cells invade new cellular territories, have a high metabolic rate, and an altered shape. The various methods to treat cancers are surgery, radiation, and chemotherapy. When the aforementioned therapies fail to achieve desired results, gene therapy is leveraged. Gene therapy involves the insertion of a functional gene, also known as therapeutic DNA, into the cells of a cancer patient to rectify the metabolism, to change or repair an acquired genetic abnormality, and to provide a new function to a cell. The two main types of gene therapy are germinal and somatic.
Global Cancer Gene Therapy Market: Key Trends
Majorly promoting the global cancer gene therapy market is the swift pace of technological breakthroughs and the growing popularity of emerging genomic technologies like next-generation sequencing and high-density DNA microarrays. Additionally, the government support for these technologies is also slated to stoke growth in the near future. The Center for Disease Control and Prevention (CDC), for example, supports screening programs for breast cancer control and cervical and colorectal cancers among low-income group women sans health insurance in the U.S.
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Besides, the rising occurrence of cancer worldwide is will substantially drive up demand for gene therapy in the years ahead. According to WHO, cases of cancer will likely touch US$15 million mark by the end of the decade.
Global Cancer Gene Therapy Market: Market Potential
At present, most of the cancer gene therapy products are in being tested. The market is predicted to grow once the trials bear results. An US pharmaceutical company named Kite Pharma, for example, recently revealed the results from the initial six months of the trial of a new gene therapy treatment called CAR-T cell therapy. It helped up patients’ own immune cells and has eliminated the disease from one third of terminal patients. Around 36 per cent of the 101 patients on the trial were still in complete remission at six months, and eight in 10 saw their cancer reduced by at least half during the study.
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Groundbreaking therapies such as this is slated to revolutionize the global cancer gene therapy market.
At present, adenoviral vector is a popular oncology application because of its effective nuclear mechanism and low pathogenicity. Adenoviral vectors are leveraged in gene replacement approaches, suicide gene, gene-based immunotherapy, and syndicate gene with chemotherapy. Retroviral vector-mediated gene transfer also plays a key role in the gene therapy industry for it brings about the crucial benefit of changing the single stranded RNA genome into a double stranded DNA molecule, which eventually integrates into the target cell genome.
Global Cancer Gene Therapy Market: Regional Outlook
North America and Europe are key regions in the global cancer gene therapy market on account of a massive elderly population and significant technological progress in the region. In the years ahead, however, the market is Asia Pacific is forecasted to surge on account of supportive government initiatives, improving economy, bettering healthcare infrastructure, and growing thrust on research and development.
Global Cancer Gene Therapy Market: Competitive Analysis
Some of the prominent players in the global cancer gene therapy market are Altor Bioscience Corporation, SiBiono., Shanghai Sunway Biotech company Limited, BioCancell, GlobeImmune, Inc.,Aduro Biotech, OncoGeneX, New Link Genetics., ZioPharm Oncology, and GENELUX. At present the market is led by small pioneering biotech firms who may eventually collaborate with prominent players for clinical development or commercialization of products.
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