Human liver grown by an Indian startup in lab

Human liver grown by an Indian startup in lab

Bengaluru, India | Red Newswire | Dec 24, 2015 Last Updated at 01:25 PM IST.
Human liver grown by an Indian startup in lab
(From letf): Abdullah Chand, Senior Scientist, Arun Chandru, co-founder and Managing Director and Sivarajan T, Senior Scientist. Image: The Hindu
Pandorum Technologies is a Bengaluru-based startup that has been successful in developing artificial tissue that can mimic functions of a real human liver.

The company says that these are 3D printed living tissues made entirely of human cells and will prove to be helpful in medical research in the sense that this would be more affordable than human and animal trials. These tissues also hold potential to be used in full organ transplantation.

Co-founder of Pandorum, Arun Chandru said that the failed human trials result because of drug metabolism and liver toxicity.

Pandorum’s mini livers will be first used as test platforms for drugs and vaccines development with less side-effects, low costs and high efficacy.

Mr. Chandru said, “We developed everything here in India. We can grow thousands of these tissues in the laboratory and test the efficacy of drugs on them for diseases including cancer.” He said around $10 billion are spent by pharma companies on research and development of a new drug.

Another co-founder of Pandorum, Tuhin Bhowmick said that such artificial organs can be used in numerous clinical applications. For example, in development of bio-artificial liver. Dr, Bhowmich who is a PhD from IISc said, “In the near future, such bio-printed organs will address the acute shortage of human organs available for surgical transplantation.”

Pandorum came into existence in 2011 after a group of friends won a business competition. Initially the team was thriving on family money and later approached Department of Biotechnology. The Biotechnology industry research Assistance Council awarded funding to the team in 2012. Same year, Bengaluru’s Centre for cellular and Molecular Platforms incubated the team.

Mr. Chandru said that creating this tissue cost them Rs. 1 Crore majority of which was funded by government.

The global market for artificial organs and bionics is expected to touch $38.75 billion by the end of 2020 as estimated by Grand View Research.

Pandorum aims at developing human organs including liver, kidney, lungs and pancreas.

Source: The Hindu